Greenville, South Carolina | City Guide for Travel Healthcare Pros
- noordinarypath
- Apr 30
- 4 min read

Welcome to Greenville, SC
Nestled in the foothills of the Blue Ridge Mountains, Greenville offers a unique blend of natural beauty and urban sophistication. With its walkable downtown, diverse culinary scene, and abundant recreational opportunities, it's an ideal destination for travel nurses seeking both professional growth and leisure activities.
💰 Cost of Living
Greenville boasts a cost of living approximately 10% lower than the national average, making it an affordable option for travel nurses. Housing costs are particularly reasonable, with expenses about 28% cheaper than the U.S. average. RentCafe
🌤️ Weather by Month
Greenville experiences a humid subtropical climate with four distinct seasons:
Month | Avg High | Avg Low | Description |
January | 52°F | 35°F | ❄️ Cool with occasional frost |
February | 57°F | 36°F | 🌤️ Mild with early signs of spring |
March | 65°F | 42°F | 🌸 Warming up with blooming flora |
April | 73°F | 50°F | 🌼 Pleasant and comfortable |
May | 80°F | 59°F | ☀️ Warm with increasing humidity |
June | 87°F | 67°F | ☀️ Hot and humid |
July | 89°F | 71°F | 🔥 Hottest month; high humidity |
August | 88°F | 70°F | 🌞 Hot with afternoon thunderstorms |
September | 82°F | 64°F | 🍂 Cooling down; less humid |
October | 73°F | 52°F | 🍁 Crisp with fall foliage |
November | 63°F | 43°F | 🌬️ Cooler with occasional rain |
December | 54°F | 36°F | ❄️ Cool with holiday charm |
🏡 Furnished Housing Options
1-Bedroom & 2-Bedroom Options
Furnished Finder – Greenville, SCOffers a variety of furnished rentals tailored for travel nurses and professionals, including private rooms and entire homes with utilities included.
Airbnb – Monthly Stays in Greenville, SCProvides fully furnished rentals with kitchens and amenities suitable for long-term stays.
Zillow – Furnished Apartments in Greenville, SCFeatures listings of furnished apartments and houses available for rent in Greenville.Trulia Real Estate Search+3Zillow+3Trulia Real Estate Search+3
Apartments.com – Furnished Apartments in Greenville, SCOffers a comprehensive list of furnished apartments with various amenities and price ranges.
Trulia – Furnished Apartments in Greenville, SCProvides listings of furnished apartments and houses, including detailed neighborhood information.
🏨 Extended Stay Hotels
Extended Stay America – Greenville – Woodruff RoadOffers suites with full kitchens, free Wi-Fi, and on-site laundry facilities.Hotels.com
WoodSpring Suites – Greenville Central I-85Provides affordable extended stay accommodations with in-room kitchens and 24/7 laundry facilities.
Residence Inn by Marriott – Greenville DowntownFeatures spacious suites with full kitchens, complimentary breakfast, and a fitness center.
stayAPT Suites – Greenville Haywood MallOffers apartment-style suites with separate living areas and full kitchens.
InTown Suites – Greenville I-85/MauldinProvides budget-friendly extended stay accommodations with in-room kitchens and weekly rates.Hotels.com
🚐 RV Parks
Springwood RV ParkLocated in Greenville, this RV park offers full hookups, laundry facilities, and a pet-friendly environment.
Travelers Rest / N Greenville KOA HolidaySituated in Travelers Rest, this KOA offers RV sites with patios, deluxe cabins, and group meeting facilities.
Shibby RV ParkLocated in Fountain Inn, this RV park provides a quiet, relaxing environment with modern amenities.ReserveAmerica+2Shibby RV Living+2RV Parky+2
🎉 Fun Things to Do in Greenville
Greenville offers a variety of activities to enjoy during your downtime:
Falls Park on the Reedy
Explore the scenic park with waterfalls, gardens, and the iconic Liberty Bridge.
Swamp Rabbit Trail
Enjoy biking or walking along this 22-mile multi-use trail.
Paris Mountain State Park
Engage in hiking, biking, and camping in this beautiful natural area.
Visit a variety of animals and participate in educational programs.
Attend concerts, Broadway shows, and other performances.
Dine at this James Beard Award semifinalist restaurant known for its small plates.Bon Appétit
Enjoy local produce, wood-fired pizzas, and a community atmosphere.Bon Appétit
Experience a unique urban farmhouse brewery with a variety of craft beers.Bon Appétit
Visit this underground speakeasy for thoughtfully crafted cocktails.Bon Appétit
🧳 Nearby Weekend Trips
Greenville's location makes it ideal for weekend getaways:
Asheville, NC: Approximately 1 hour away, explore the Blue Ridge Mountains and vibrant arts scene.
Atlanta, GA: Around 2.5 hours away, experience a bustling city with diverse dining and entertainment options.BestPlaces+13Furnished Finder+13Southern Living+13
Charlotte, NC: Just under 2 hours away, enjoy shopping, museums, and cultural attractions.
Charleston, SC: About 3.5 hours away, immerse yourself in historic charm and coastal beauty.
Great Smoky Mountains National Park: Approximately 2.5 hours away, engage in hiking, wildlife viewing, and scenic drives.
🧭 Summary
Greenville, South Carolina, offers travel nurses a unique blend of professional opportunities and recreational activities. With its scenic beauty, rich history, and welcoming community, it's an excellent choice for your next assignment.
✅ Affordable cost of living
✅ Four distinct seasons with outdoor activities year-round
✅ Variety of furnished housing and extended stay options
✅ Proximity to major Southeastern attractions
✅ Vibrant local culture and events
Whether you're exploring historic sites, enjoying outdoor adventures, or immersing yourself in community events, Greenville provides a fulfilling and enjoyable experience for travel nurses.
Disclosure: The information provided in this guide is what I use to send my travelers and is obtained through ChatGPT, utilizing prompts I frequently use as a travel nurse recruiter. The content is designed to help travelers make informed decisions about potential destinations.
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